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Immunotherapy which focuses on the upregulation of the immune system's ability to target and destroy cancer cells is at the forefront of experimental cancer therapy today. Immunization, in particular, is currently one of the most promising approaches to immune therapies in treating cancer.
The idea of a therapeutic vaccine to treat cancer is not new. Researchers have studied and debated the possibility of vaccinating against cancer for decades. Only in recent years has the debate changed from whether or not it is possible, to what defines a tumor antigen and how to optimally deliver such a vaccine to induce anti-cancer activity.
Vaccines consisting of peptides derived from the protein sequences of tumor-specific antigens represent the vast majority of cancer vaccine research. Peptide-based cancer vaccines were among the first vaccines identified which demonstrated both protective and therapeutic benefit in animal models. They currently account for the majority of clinical trials addressing biological cancer therapy.
Research on the development of peptide-based vaccines including the identification of candidate peptides, strategies for improving peptide delivery as well as data from clinical trials which utilize peptide-based vaccines is becoming more and more available. The aim of this vaccine approach utilizes nano-isolation technology of proteins, buffy elements, serum, blood and body fluids to amplify the immune system's cancer fighting response. Continued research is showing the field of immune-amplification to be a very promising therapy.
The research at HWICRG is applied in a multi-stemmed treatment approach geared toward optimization of the immune response. Conjuntice therapies include IV therapy, oral supplementation, nutritional therapy and the use of immune-amplification autologous vaccines. The focus of these therapies is to complement each other in a multiude of ways that, together, both upregulate body's immune response and make it more target-specific.